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Music as medicine: simple listening may ease stroke aftermath

NCT ID NCT06743412

Symptom relief Sponsor: IRCCS Ospedale San Raffaele Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether listening to self-chosen Italian music during and after a stroke hospital stay can improve mood, reduce anxiety and depression, and boost overall well-being. 150 stroke patients were randomly assigned to either regular music listening or standard care. The goal was to see if this simple, pleasant activity could make a real difference in recovery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
regular listening of self-selected Italian music
What this could lead to
If it works, this could offer a simple, low-cost way to improve mood and quality of life for stroke patients during recovery.
What could go wrong
This is a small, single-center study with no blinding, so results may be biased. The intervention is just music listening, so any benefits are likely modest and may not apply to all stroke patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

150 people

The number who actually took part.

Started

Jun 2022

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * time of enrollment greater than 24 hours and less than 4 days from onset of acute cerebrovascular disease * native Italian speaker * able to cooperate according to the following criteria: * NIHSS stroke severity score at enrollment \<10. * No impairment in alertness, orientation, or language that would prevent adequate communication (NIHSS score \<2 for items 1a, 1b, 1c, 9, 10). * No known pre-existing severe or moderate cognitive decline (CDR\<2). * potentially able to continue music listening after discharge. * papable of giving informed consent for the study. Exclusion Criteria: * Deafness and/or significant hearing loss and/or significant visual impairment and/or illiteracy. * Major psychiatric illness. * Other conditions that, in the investigator's judgment, would prevent compliance with the protocol during hospitalization or the post-hospitalization phase.

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Conditions

The condition(s) this trial relates to.

hemorrhagic stroke ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute stroke

Contacts and locations

Locations

  • IRCCS Ospedale San Raffaele

    Milan, 20132, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.