Cancer patients face a hidden Second-Stroke threat, and 24 hospitals are mapping it
NCT ID NCT07819526
First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time
Summary
Researchers at 24 hospitals in Japan are following 500 people who had an acute ischemic stroke while also living with active cancer. The study measures how often a second stroke occurs within three months and which clinical factors, such as cancer type, stroke features, and test results, may be linked to recurrence. Participants receive standard care from their own doctors; researchers only collect information and do not assign any treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If researchers learn which factors predict a second stroke in people with cancer, doctors could one day target monitoring and prevention more precisely for this group.
- What could go wrong
- This is an observational study, so it can only show patterns and associations, not cause and effect. The findings may not apply to patients outside Japan or to cancers not represented in the group.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Mar 2032
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of participants with acute ischemic stroke and active cancer who receive medical care at participating hospitals in Japan. Eligible participants will be enrolled prospectively during the study enrollment period.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Acute ischemic stroke diagnosed within 7 days after symptom onset or the time last known well. 2. Active cancer at the time of the index stroke, as defined below. Exclusion Criteria: 1. The patient or a legally acceptable representative indicates that the patient does not wish to participate. 2. The investigator considers enrolment inappropriate.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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The Univeristy of Osaka
RECRUITINGSuita, Osaka, 565-0871, Japan
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