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Radiotherapy's hidden toll: muscle loss and fatigue under the microscope

NCT ID NCT02567669

First seen Mar 21, 2026 · Last updated Jun 23, 2026 · Updated 14 times

Summary

This study tracks 20 women with breast cancer to see if radiotherapy causes muscle loss outside the treated area and how it relates to fatigue. Participants complete fatigue questionnaires and get CT scans at four time points: start, end, and 1 and 3 months after treatment. The goal is to understand these side effects better, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors understand why some patients feel tired and lose muscle during radiotherapy, leading to better supportive care.

What could go wrong

This is a small, observational study with only 20 participants, so results may not apply to everyone. It is not testing a treatment, so no direct benefit for patients.

Conditions

The condition(s) this trial relates to.

breast neoplasm Fatigue Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.