Scientists probe muscle repair secrets with growth hormone and zaps
NCT ID NCT05746650
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at how connective tissue in muscles and tendons repairs itself after an injury. Forty people scheduled for knee surgery will receive either growth hormone or a placebo, with or without electrical stimulation to their hamstring muscles. Researchers will measure protein production in the tissue to understand the repair process.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Growth hormone (somatropin)
- What this could lead to
- If successful, this could help scientists understand how muscles and tendons repair after injury, potentially leading to better treatments for muscle injuries.
- What could go wrong
- This is a small, early-stage study focused on measuring biological processes, not on proving a treatment works. The results may not lead to any direct medical benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2023
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy men and women scheduled to undergo reconstructive knee surgery * BMI 18-35 Exclusion Criteria: * Former or current use of growth hormone or anabolic steroids * Use of corticosteroids in the past 3 months * Use of any medication known to affect muscle or tendon turnover * Former participation in a study using deuterated water * Chronic diseases
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Bispebjerg Hospital
RECRUITINGCopenhagen, 2400, Denmark
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