Can tailored therapy help teens with behavioral issues and intellectual disabilities?
NCT ID NCT06032455
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a special version of multisystemic therapy (MST-ID) works better than standard therapy for teenagers (ages 10-19) with severe behavioral problems who come from families with intellectual disabilities. About 470 teens and their families will take part, filling out questionnaires at the start, end, and up to 18 months after therapy. The goal is to see if MST-ID reduces rule-breaking behavior more effectively and to understand families' experiences with the treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 470 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2023
- Expected to finish
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Sep 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The target population consists of adolescents and their parent(s) with a known or suspected ID referred to MST-ID at one of three Dutch mental health care organisations (de Viersprong, Koraal, and Prisma) or to standard MST at one of two Dutch mental health care organisations (de Viersprong and Pactum).
- Ages
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10 to 19 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Referral Criteria: * Known or suspected ID of the referred adolescent and/or their parent(s); * Educational level of the referred adolescent and/or highest attained diploma of their parent(s) is indicative of potential ID. Inclusion Criteria Study Sample: * Adolescent must be 10 to 19 years old at the start of treatment; * Adolescent presents with severe behavioural problems in at least two life areas; * Adolescent lives with a family or there is a family the adolescent can live with, in which parent(s) have parental custody for a longer period of time; * Parent(s) consent(s) and is/are willing to engage in treatment to prevent an out-of-home placement of the adolescent; * Adolescent and/or parent(s) have a known or suspected intellectual disability (operationalised as an intelligence quotient \[IQ\] score of between 50-85 and additional deficits in adaptive functioning) * Adolescent and/or parent(s) have sufficient knowledge of the Dutch language (as assessed by a clinician and/or researcher) in order to understand and answer the various (self-report) questionnaires. Exclusion Criteria Study Participation: * Adolescent lives independently; * Adolescent presents with severe problematic sexual behaviours, without presenting with other severe behavioural problems; * Adolescent presents suicidal, psychotic, or homicidal requiring specialised treatment (such as a crisis placement in a residential facility); * Adolescent has a severe Autism Spectrum Disorder (level 2-3 according to the Diagnostic and Statistical Manual of Mental Disorders \[DSM-V\] criteria) or a severe ID (IQ score \<50); * Adolescent has internalising psychiatric problems which are the primary reason for referral, or has serious psychiatric problems (similar to #3 as well as for example eating disorder.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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De Viersprong
RECRUITINGHalsteren, Netherlands
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Koraal
RECRUITINGSittard, Netherlands
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Pactum
RECRUITINGZetten, Netherlands
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Stichting Prisma
RECRUITINGWaalwijk, Netherlands
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