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Could your gums reveal clues about multiple sclerosis?

NCT ID NCT07412431

Knowledge-focused Sponsor: Saglik Bilimleri Universitesi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study will check the gum health of 100 people—half with multiple sclerosis (MS) and half without—by measuring gum pockets, plaque, and inflammation. Researchers will also test saliva for certain bacteria and viruses to see if they are linked to MS. The goal is to better understand how MS and gum disease might be connected.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could reveal a connection between MS and gum disease, pointing toward new ways to monitor or manage MS through oral health.
What could go wrong
This is an observational study, not a treatment trial. It is small (100 people) and not yet recruiting, so results may not apply broadly or lead to direct benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of patients diagnosed with Multiple Sclerosis who are followed by the Neurology Department of Ankara Bilkent City Hospital, and age-and-gender-matched systemically healthy volunteers as a control group.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria (Test Group): * Voluntarily agreeing to participate in the study. * Being over 18 years of age. * Diagnosed with Multiple Sclerosis (MS) according to the 2017 McDonald criteria. * Being able to communicate clearly and effectively. Inclusion Criteria (Control Group): * Voluntarily agreeing to participate in the study. * Being over 18 years of age. * Not having a diagnosis of Multiple Sclerosis (MS) according to the 2017 McDonald criteria. * Being able to communicate clearly and effectively. Exclusion Criteria (Test Group): * Being under 18 years of age. * Patients whose MS diagnosis is not yet definitive. * Being pregnant or in the lactation (breastfeeding) period. * Having received antibiotic treatment within the last 3 months. * Having received periodontal treatment within the last 6 months. * Patients undergoing radiotherapy or chemotherapy. Exclusion Criteria (Control Group): * Being under 18 years of age. * Being diagnosed with Multiple Sclerosis (MS) according to the 2017 McDonald criteria. * Being pregnant or in the lactation (breastfeeding) period. * Having received antibiotic treatment within the last 3 months. * Having received periodontal treatment within the last 6 months. * Patients undergoing radiotherapy or chemotherapy.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis Periodontitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.