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Can brain energy issues predict nerve damage in MS?

NCT ID NCT04532944

First seen Jun 05, 2026 · Last updated Jun 22, 2026 · Updated 3 times

Summary

This study uses advanced MRI scans to look at energy use in the brains of people with multiple sclerosis (MS) and healthy volunteers. The goal is to see if early energy problems in brain cells can predict nerve damage over two years. Researchers hope this will help understand how MS causes disability and lead to new treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ICM, Hôpital Pitié Salpêtrière, 47 Boulevard de l'Hôpital

    Paris, 75013, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help identify early signs of nerve damage in MS, paving the way for new treatments that protect the brain.

What could go wrong

This is an observational study, not a treatment trial. It may not directly lead to new therapies, and results may not apply to all MS patients.

Conditions

The condition(s) this trial relates to.

multiple sclerosis Nerve Degeneration

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.