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MRSA prevention: could a clean home and medicated wash stop infections?

NCT ID NCT02572791

Prevention Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether combining personal hygiene (using medicated washes and ointments) with household cleaning can prevent MRSA skin infections. Over 800 people from households with a recent MRSA infection took part. The goal was to see if this combined approach reduces the spread of MRSA and lowers the number of new infections.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Chlorhexidine (Hibiclens) and Mupirocin (Bactroban) plus household cleaning
What this could lead to
If successful, this could point toward a practical, at-home strategy to reduce MRSA infections in households with affected members.
What could go wrong
This is a completed Phase 4 trial, but results may not apply to all populations or settings. The interventions require consistent adherence, which may be challenging in real life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

835 people

The number who actually took part.

Start date

Oct 2015

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Up to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients 18 years of age and younger * Confirmed (i.e., culture-positive) active or recent (within the past 2 months) S. aureus cutaneous infections * Reside within 75 miles of St. Louis Children's Hospital * Provide written, informed consent, or consent is provided by a parent or legal guardian Exclusion Criteria: * Patients with nosocomial infections (i.e., \>48 hours after hospitalization) * Patients with traditional risk factors for HA-MRSA (e.g., immunodeficiency, indwelling catheter or percutaneous medical device, undergoing dialysis, presenting with a surgical site infection, or residing in a long-term care facility within the past year). * Patients who are unable to give consent or for whom consent is not obtained * Patients refusing home environmental cultures by the study team * Patients without a permanent home (e.g., living in a shelter or group home)

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Conditions

The condition(s) this trial relates to.

skin disease caused by bacterial infection staphylococcal infection staphylococcus aureus infection methicillin-resistant staphylococcus aureus infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MRSA - methicillin resistant staphylococcus aureus infection Skin and subcutaneous tissue bacterial infections Staphylococcus aureus

Contacts and locations

Locations

  • St. Louis Children's Hospital

    St Louis, Missouri, 63110, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

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