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New mRNA flu shot passes first safety test in humans

NCT ID NCT05426174

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 27 times

Summary

This early-stage study tested a new mRNA-based flu vaccine in 233 healthy adults aged 18 and older. The goal was to check if the vaccine is safe and triggers an immune response. Participants received one shot and were monitored for side effects like reactions at the injection site or other symptoms. The study is now complete, and results will help decide if further testing is needed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • AES - DRS - Optimal Research_Site 8400001

    Peoria, Illinois, 61614-4885, United States

  • AES - DRS - Optimal Research_Site 8400002

    Melbourne, Florida, 32934-8172, United States

  • AES - DRS - Optimal Research_Site 8400007

    Huntsville, Alabama, 35802, United States

  • Central Phoenix Medical Clinic, LLC_Site: 8400010

    Phoenix, Arizona, 85020, United States

  • Optimal Research San Diego, LLC_Site: 8400009

    San Diego, California, 92108, United States

  • Synexus Clinical Research_Site 8400003

    Cincinnati, Ohio, 45236, United States

Conditions

Explore the condition pages connected to this study.