No more nasty drinks? MRI study aims to ease Crohn's scans
NCT ID NCT07471438
First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 2 times
Summary
This study looks at whether an MRI without a bowel-distending drink (like PEG or mannitol) can still accurately measure inflammation in the small bowel of people with Crohn's disease. Many patients find these drinks hard to tolerate, causing vomiting or diarrhea. If skipping the drink works just as well, it could make follow-up scans much more comfortable for patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2026
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with Crohn's disease according to European recommendations (ECCO) ≥ 18 years of age * With known or suspected ileal ± colonic involvement * Requiring reassessment of disease inflammatory activity according to the clinician * Able to give informed consent to participate in the research. * Affiliation with a Social Security scheme * Agreeing to undergo two MRIs in the same week Exclusion Criteria: * Isolated colonic Crohn's disease * Resection \> 1 m of small intestine * Severe obstructive symptoms defined according to CDOS (Crohn's disease obstructive symptoms score) * Uncontrolled intra-abdominal abscess * Isolated anoperineal lesions * Prevention of postoperative endoscopic recurrence * Temporary or permanent stoma * Total colectomy * Contraindication to MRI * Pregnant or breastfeeding women * Protected adults (under guardianship, trusteeship, family authorization, future protection mandate, with representation relating to the person)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU d'Amiens
RECRUITINGAmiens, France
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CHU de Clermont-Ferrand
NOT_YET_RECRUITINGClermont-Ferrand, 63000, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can tissue clues predict which Crohn's patients relapse after surgery?
- Exercise as a potential remedy for IBD-related fatigue
- AI reads capsule endoscopy videos to hunt for Crohn's lesions
- Can a simple ultrasound replace MRI for fistula diagnosis?
- A 7,000-person study hunts for hidden clues that predict Crohn's and colitis