Could regular MRIs replace invasive biopsies for prostate cancer monitoring?
NCT ID NCT06280781
First seen Apr 10, 2026
Summary
This study compares regular MRI scans to standard care for men with low- to medium-risk prostate cancer who choose active surveillance (monitoring instead of immediate treatment). The goal is to see if MRIs can detect cancer progression earlier and more accurately, potentially reducing the number of biopsies and other tests. Over 1,200 participants will be followed for 5 years to measure cancer progression rates and cost-effectiveness for the NHS.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Locations
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Bradford Royal Infirmary
RECRUITINGBradford, United Kingdom
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Charing Cross Hospital
RECRUITINGLondon, W6 8RF, United Kingdom
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Darent Valley Hospital
RECRUITINGDartford, Kent, DA2 8DA, United Kingdom
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Freeman Hospital
RECRUITINGNewcastle upon Tyne, United Kingdom
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Glan Clywd Hospital
RECRUITINGRhyl, United Kingdom
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Heatherwood Hospital
RECRUITINGAscot, Berkshire, SL5 7GB, United Kingdom
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Kings College London
RECRUITINGLondon, United Kingdom
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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North Cumbria
RECRUITINGWhitehaven, United Kingdom
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Northern Lincolnshire and Goole NHS Foundation Trust
RECRUITINGScunthorpe, United Kingdom
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Southampton University Hospital
RECRUITINGSouthampton, United Kingdom
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St Peter's Hospital
RECRUITINGChertsey, United Kingdom
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West Middlesex Hospital
RECRUITINGLondon, United Kingdom
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
MRI scans
What this could lead to
If successful, regular MRI scans could become the new standard for monitoring low- to medium-risk prostate cancer, catching progression earlier and reducing the need for invasive biopsies.
What could go wrong
This is a large trial but still ongoing, and results may show that regular MRIs don't significantly improve detection or are not cost-effective for the NHS. MRI also has limitations and may miss some cancers.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.