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New MRI technique could sharpen MS diagnosis

NCT ID NCT04705870

Diagnosis Sponsor: Fondation Ophtalmologique Adolphe de Rothschild Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two different MRI scanning methods to see which better detects the 'central vein sign' in the brains of people with multiple sclerosis (MS). The central vein sign is a marker that helps doctors diagnose MS more accurately. Sixty adults with early-stage MS underwent extra MRI sequences during their routine scan. The goal was to compare a standard fast MRI with a newer, higher-resolution version to see if the newer one finds more of these signs.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cerebral MRI (device)
What this could lead to
If successful, this could lead to more accurate and faster MRI-based diagnosis of multiple sclerosis.
What could go wrong
This is a small, completed study focused on comparing imaging techniques, not a treatment. Results may not change current practice without larger validation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Jun 2021

Finished

May 2023

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patient with MS and who should undergo an MRI examination with or without injections of contrast agent as part of their care.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over 18 * With MS defined according to the McDonald's revised clinical or radiological spatial and temporal dissemination criteria, with onset of symptoms \<5 years * To benefit as part of care from an MRI with or without injection of gadolinium * Express consent to participate in the study * Affiliate or beneficiary of a social security scheme Exclusion Criteria: * Patient benefiting from a legal protection measure * Pregnant or breastfeeding woman

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Multiple sclerosis

Contacts and locations

Locations

  • Hhopital fondation adolphe de rothschild

    Paris, Paris, 75019, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.