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MRI-Guided radiation aims to safely boost liver tumor treatment

NCT ID NCT04020276

First seen Jan 10, 2026 · Last updated Jun 23, 2026 · Updated 16 times

Summary

This early-phase trial is testing whether MRI-guided radiation therapy (SBRT) can be given at higher doses safely to people with cancer that has spread to the liver. Up to 32 participants will receive 5 radiation sessions over 1.5 to 2 weeks. The main goal is to find the highest dose that does not cause serious side effects within the first month.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Wisconsin

    RECRUITING

    Madison, Wisconsin, 53792, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic Body Radiation Therapy (SBRT) with real-time MRI guidance

What this could lead to

If successful, this could establish a safer, more effective radiation dose for treating liver metastases, potentially improving tumor control with fewer side effects.

What could go wrong

This is an early phase I trial with only 32 participants, focused on safety and dosing. It may not lead to better outcomes, and there is a risk of radiation-related toxicity.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.