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New combo therapy shows promise for follicular lymphoma patients

NCT ID NCT04246086

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 31 times

Summary

This study tests a combination of two drugs, mosunetuzumab and lenalidomide, in people with follicular lymphoma, a type of blood cancer. The goal is to see if the combo is safe and works better than standard treatments. About 237 adults whose cancer has returned or needs treatment will take part. The study also compares giving one drug as a shot under the skin versus through an IV.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • CHU Rennes - Hopital Pontchaillou

    Rennes, 35033, France

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • City of Hope National Medical Center

    Duarte, California, 91010, United States

  • Cleveland Clinic

    Cleveland, Ohio, 44195-0001, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710-4000, United States

  • Fairview Hospital

    Cleveland, Ohio, 44111, United States

  • Freeman Hospital

    Newcastle upon Tyne, NE7 7DN, United Kingdom

  • Fudan University Shanghai Cancer Center

    Shanghai, 200120, China

  • Hillcrest Hospital

    Mayfield Heights, Ohio, 44124, United States

  • Hospital Universitario Fundacion Jimenez Diaz.

    Madrid, 28040, Spain

  • Hospital Universitario Virgen de la Victoria

    Málaga, 29010, Spain

  • Mary Bird Perkins Cancer Ctr

    Baton Rouge, Louisiana, 70809, United States

  • Norton Cancer Institute - St. Matthews

    Louisville, Kentucky, 40207-4723, United States

  • Nottingham University Hospitals NHS Trust - City Hospital

    Nottingham, NG5 1PB, United Kingdom

  • Rhode Island Hematology/Oncology Program

    Woonsocket, Rhode Island, 02895-4720, United States

  • Swedish Medical Center

    Seattle, Washington, 98122, United States

  • Tennessee Oncology PLLC - Franklin

    Franklin, Tennessee, 37067, United States

  • Tennessee Oncology;Chattanooga Oncology & Hematology Associates

    Chattanooga, Tennessee, 37404, United States

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • The First Affiliated Hospital of Xiamen University

    Xiamen, 361003, China

  • The First Hospital of Jilin University

    Changchun, 130021, China

  • Tianjin Medical University Cancer Institute & Hospital

    Tianjing, 300060, China

  • University College London Hospitals NHS Foundation Trust - University College Hospital

    London, NW1 2PG, United Kingdom

  • University of Miami Miller School of Medicine

    Miami, Florida, 33136-1002, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109, United States

  • West China Hospital, Sichuan University

    Chengdu, 610041, China

Conditions

Explore the condition pages connected to this study.