C-Section pain study: which morphine works best?
NCT ID NCT07386353
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways of giving morphine after a planned C-section: through a shot in the spine (intrathecal) or through a small tube near the spine (epidural). The goal is to find which method provides better pain relief with fewer side effects like nausea or itching. About 120 women having elective C-sections will take part.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 120 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2024
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Pregnant women scheduled for elective cesarean section; * Age \> 18 years; * Willingness to participate in the study, as demonstrated by signed informed consent. Exclusion Criteria: * American Society of Anesthesiologists (ASA) physical status classification \> III; * Chronic kidney disease with a glomerular filtration rate \< 60 mL/min; * Relevant drug allergies (particularly to protocol medications); * Opioid tolerance; * Contraindication to neuraxial anesthetic techniques.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Central do Funchal
RECRUITINGFunchal, Madeira, 9004-514, Portugal
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