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Scientists hunt for hidden genes behind mysterious fevers

NCT ID NCT05364294

First seen Mar 07, 2026 · Last updated Jun 20, 2026 · Updated 13 times

Summary

This study is looking for new genes and biological markers that cause systemic autoinflammatory diseases (SAIDs), a group of rare conditions that cause repeated fevers and inflammation. Researchers will analyze the DNA and blood of 300 patients to find disease-causing mutations and understand how these diseases work. The goal is to improve diagnosis and eventually offer more personalized treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Trousseau Hospital

    RECRUITING

    Paris, 75012, France

    Contact Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to better genetic tests and personalized treatment options for people with rare autoinflammatory diseases.

What could go wrong

This is an early-stage observational study focused on understanding the disease, not testing a treatment. It may not directly benefit participants and results may take years to translate into clinical practice.

Conditions

The condition(s) this trial relates to.

autoinflammatory syndrome hereditary disease inflammatory disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.