INFLAMMATORY DISEASE

This study tests whether a comprehensive treatment plan can reduce serious heart events in people with rapidly-progressive coronary artery disease driven by inflammation. Researchers will compare each participant's outcomes before and after treatment. The study enrolls 39 adults …

This study is testing a new imaging agent called 68Ga-FAPI46 to see if it can improve how doctors detect and monitor chronic inflammatory and fibrotic diseases like rheumatoid arthritis, liver fibrosis, and lupus. About 390 adults with these conditions will receive a PET/CT scan …

This study aims to learn more about heart and blood vessel diseases by observing people who have them or are at risk. Researchers will collect blood, tissue, and perform imaging tests like MRI and CT scans. The goal is to improve diagnosis and understanding of these conditions. P…

This study is for people with a type of heart disease linked to inflammation. Researchers want to learn about the symptoms, treatments, and health outcomes of 120 participants. The goal is to better understand this condition, not to test a new treatment.

This study looks at how the body processes high doses of the steroid prednisolone in people with inflammatory diseases like thyroid eye disease, asthma, and vasculitis. Researchers will measure drug levels in the blood and urine to compare short-term and long-term use. The goal i…

This study looks at how small changes in your genes might affect the body's natural ability to control inflammation. Inflammation is a normal response to injury or illness, but when it goes unchecked, it can lead to diseases like rheumatoid arthritis and heart problems. Researche…

This study aims to understand why some people with coronary artery disease get worse quickly due to inflammation. Researchers will compare 20 patients with inflammation-linked rapid disease to 10 patients with standard disease. They will look at medical history, lab tests, and im…

This study looks for new genes and biological clues in 300 people with rare autoinflammatory diseases (SAIDs). Researchers will use advanced genetic testing and blood analysis to find disease-causing mutations and unique immune patterns. The goal is to better understand these con…

This study collects DNA samples from 1200 adults receiving routine care at the University of Chicago. Researchers test for genetic differences that could affect how patients respond to certain medications, including risk of side effects. The results are shared with their doctors,…