Dental implants may improve diabetes control, new trial suggests

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged between 18 and 75 years * Type 2 diabetes diagnosed for more than 6 months, according to the diagnostic criteria of the International Diabetes Federation * Insufficiently controlled type 2 diabetes (HbA1c between 7.5% and 10.5%) * Type 2 diabetes under stable treatment for at least 3 months (no initiation or discontinuation of antidiabetic treatments, and no change in basal insulin dose greater than ±50% compared with the initial dose) * Presence of all teeth up to the second premolars, i.e. presence of maxillary and mandibular incisors, canines and premolars. The absence of premolars extracted for orthodontic reasons or due to agenesis is not taken into account. Teeth replaced by fixed tooth- or implant-supported prostheses are considered present. * Absence of functional molar pairs not compensated by a partial prosthesis, or presence of only one functional molar pair. The absence of a pair may be due to the absence of both molars or only one molar (molar without an antagonist). Third molars are not taken into account. Exclusion Criteria: * Recent diabetes (\< 6 months), intensified insulin therapy (≥ 3 injections/day) or insulin pump use * Type 1 diabetes * Type 2 diabetes with HbA1c \> 10.5% * Comorbidities contraindicating part of the oral rehabilitation (particularly implant placement) or impacting masticatory efficiency, such as end-stage renal disease or stroke within the past 6 months * Smoking \>10 cigarettes/day * Presence of severe crestal defects, insufficient prosthetic space, malocclusions and/or parafunctions contraindicating part of the oral rehabilitation * Severe periodontitis (Stage III or IV, Grade C) * Cancerous or precancerous lesions of the oral mucosa * Allergy to anesthetics or antibiotics required for dental surgery * Pregnant or breastfeeding woman * Participation in another interventional study involving human participants or being within the exclusion period following a previous study involving human participants, where applicable * No affiliation to a social security scheme * Patient benefiting from State Medical Aid (AME) * Individual deprived of liberty or under legal protection measures * Refusal or inability to provide written informed consent