Heart valve mystery: 1,900-Patient study aims to spot who needs early help
NCT ID NCT06789211
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study follows 1,900 people with moderate mixed aortic valve disease (a combination of valve narrowing and leaking) to see how symptoms and heart function relate to survival. Researchers hope to identify high-risk patients who might benefit from valve surgery or catheter procedures, even though current guidelines don't recommend intervention at this stage. The study is purely observational, meaning no new treatment is being tested.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MIXED AORTIC VALVE DISEASE are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Leiden University Medical Center
RECRUITINGLeiden, South Holland, 2333ZA, Netherlands
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors identify which patients with moderate mixed aortic valve disease need early valve intervention, potentially improving survival and quality of life.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly test any new therapy. Results may not lead to immediate changes in care, and findings might not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.