Large study aims to clarify risks for patients with mixed aortic valve disease
NCT ID NCT06789211
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This observational study will follow 1900 people with moderate mixed aortic valve disease (a combination of aortic stenosis and regurgitation) to see how symptoms and heart function relate to survival and the need for valve replacement. Researchers hope to identify which patients are at higher risk and might benefit from earlier intervention. Currently, there are no clear guidelines for treating this condition, so the study aims to fill that knowledge gap.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help doctors identify which patients with moderate mixed aortic valve disease might benefit from early valve intervention, potentially improving survival and quality of life.
- What could go wrong
- This is an observational study, not a treatment trial, so it will not directly test any new therapy. The results may only confirm current uncertainty and not lead to immediate changes in care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Leiden University Medical Center
RECRUITINGLeiden, South Holland, 2333ZA, Netherlands