New procedure aims to stop brain bleeds from coming back
NCT ID NCT06163547
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This trial tests a procedure called middle meningeal artery (MMA) embolization for people with chronic subdural hematomas—a buildup of blood on the brain that can cause confusion and weakness. The study will see if blocking the artery that feeds the hematoma can prevent it from returning after surgery or even treat it without surgery. About 180 adults with symptomatic or stubborn hematomas will take part across multiple centers.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Middle meningeal artery embolization (a minimally invasive procedure that blocks blood flow to the hematoma)
- What this could lead to
- If it works, this could offer a less invasive way to treat chronic subdural hematomas and reduce the need for repeat surgeries.
- What could go wrong
- This is a mid-stage trial with 180 participants, so results are not yet proven. The procedure carries risks like bleeding or allergic reaction to contrast dye, and it may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2025
- Expected to finish
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Jan 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age: 18-100 * Consent possible * cSDH located at the convexities * Patients with symptomatic cSDH * Patients with asymptomatic large chronic/subacute hematoma after 6 weeks of failed conservative treatment Exclusion Criteria: * Consent not possible * Pregnancy * Prisoner * Angiography contraindication * Patient for whom follow-up is problematic (e.g. distant residency, homeless …) * Previous surgery for cSDH
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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EOC
RECRUITINGLugano, Switzerland
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Geneva University Hospitals
RECRUITINGGeneva, Switzerland
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Hidden infection may drive dangerous brain bleed recurrence in seniors
- Liquid embolization may offer Needle-Free alternative to brain surgery for blood clots
- Simple surgical trick may cut repeat brain surgery in older adults
- New recovery pathway aims to cut repeat surgeries for brain bleed in elderly