New hope for kids with brain tumors: drug that crosses the Blood-Brain barrier shows promise
NCT ID NCT04923126
First seen Feb 04, 2026 · Last updated Jun 18, 2026 · Updated 21 times
Summary
This study tests a drug called mirdametinib, which is designed to reach the brain and target a key growth signal in low-grade glioma cells. It is for children, adolescents, and young adults (ages 2 to 24) whose tumor has come back or is growing. The goal is to find the best dose and see if the drug can shrink or stabilize the tumor. While not a cure, it may help control the disease and improve outcomes.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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St. Jude Children's Research Hospital
RECRUITINGMemphis, Tennessee, 38105, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.