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New hope for UC patients: early biologic therapy may outperform standard care

NCT ID NCT07235904

First seen Nov 19, 2025 · Last updated Apr 24, 2026 · Updated 21 times

Summary

This study compares early treatment with mirikizumab (a biologic) to the standard approach with azathioprine in 300 adults newly diagnosed with moderate-to-severe ulcerative colitis. Participants are randomly assigned to receive either mirikizumab or azathioprine for 52 weeks. The goal is to see if starting with mirikizumab leads to better disease control, including remission without steroids, improved quality of life, and fewer side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospital Schleswig-Holstein

    RECRUITING

    Kiel, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.