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Breakfast shake study reveals how fats may tweak your immune system

NCT ID NCT07502898

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 27, 2026 · Updated 2 times

Summary

This study looks at how eating fat every day from either dairy or plants changes the body's immune response. Thirty-nine healthy adults aged 40-70 will drink a high-fat shake and have blood tests before and after a month of daily smaller shakes. The goal is to see if repeated fat exposure alters inflammation markers like IL-6.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
breakfast shakes containing dairy-derived or plant-derived lipids
What this could lead to
If successful, this could help explain how different types of dietary fat influence inflammation over time, potentially guiding future dietary recommendations.
What could go wrong
This is a small, early-stage study in healthy volunteers, not a treatment trial. Results may not apply to people with health conditions, and the findings are exploratory.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

39 people

The number who actually took part.

Started

Jan 2026

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Apparently healthy man or woman * Age 40-70y at the time of screening * BMI of 22-27 kg/m2 * Having a Hb value above 8.4 (men) or 7.4 (women) mmol/L * Having veins suitable for blood sampling via a catheter cannula (judged by study nurse/ medical doctor) * Willing to have dairy-based breakfast every day * Having a mobile phone suitable for installing the research app * Signed informed consent and able to adhere to the protocol Exclusion Criteria: * A history of cardiovascular diseases, such as a stroke or heart disease; * Having an eating disorder; * Having diabetes (type I or type II); * Having used antibiotics in the past 3 months; * Using diabetes medication; * Using medications that may affect the study results (as assessed by the study physician); * Suffering from stomach or intestinal problems, such as Crohn's disease, ulcerative colitis, irritable bowel syndrome, or having undergone major digestive system surgery; * Having known food allergies or intolerances to foods used in the study (e.g., cow's milk); * Having an Hb level of less than 8.5 mmol/L (for men) or less than 7.5 mmol/L (for women) - to be tested during the eligibility assessment; * Being allergic or intolerant to medical skin patches; * Suffering from chronic or acute inflammatory diseases, such as rheumatoid arthritis or psoriatic arthritis; * Having an autoimmune disease; * Having thyroid problems; * Having recently donated blood (within 2 months before the eligibility assessment) or planning to donate blood during the study period; * Having recently participated in another medical-scientific study (within 2 months before the eligibility assessment); * Suffering from severe kidney or liver problems or a chronic kidney or liver disease; * Following a specific diet that may affect the results or is unsuitable for the study, such as a vegan diet; * Using tobacco/drugs or smoking (including snus and/or vaping); * Drinking more than 14 (for women) or 21 (for men) alcoholic drinks per week; * Being pregnant, planning to become pregnant, or breastfeeding; * Gained or lost more than 5 kg body weight in the past 3 months; * Intention to lose or gain more than 5 kg during the study period; * Intention to change exercise intensity during the study period; * Not having a mobile phone suitable for using a research application; * Having another serious medical condition that may interfere with participation, thus being deemed unsuitable for participation in the study as assessed by the study physician or principal investigator (e.g., displaying inappropriate behavior); * Inability to comply with the study diet * Inability to understand study information/communicate with staff; * Being employed or doing an internship at the Department of Human Nutrition and Health of Wageningen University or FrieslandCampina.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Wageningen University

    Wageningen, 6708WE, Netherlands

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