Mindfulness may ease anxiety for seniors with memory worries
NCT ID NCT03005652
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether an 8-week mindfulness program could reduce anxiety in 168 older adults who have memory concerns but normal cognitive test scores. Participants were randomly assigned to either mindfulness training or a health education program. The goal was to see if mindfulness could improve mental health and potentially slow future cognitive decline.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- mindfulness training
- What this could lead to
- If it works, this could offer a drug-free way to ease anxiety in people worried about their memory, potentially slowing cognitive decline.
- What could go wrong
- This is a completed study with 168 participants, so results are limited. The benefit may be small or not last long, and mindfulness requires time and effort.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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168 people
The number who actually took part.
- Started
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Apr 2017
- Finished
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Sep 2018
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged ≥ 60 years * Meet the research criteria proposed by the international SCD-I working group for studies in SCD * Performance within the normal range on standardised cognitive tests according to agreed study-specific standards to rule out mild cognitive impairment (MCI) and dementia * Either referred to the memory clinic by a physician or who are self-referrals because of memory concerns (assessed by a positive response to the question 'Are you worried about your memory?') * Ability to provide informed consent in accordance with International Conference on Harmonization of Good Clinical Practice (GCP/ICH) guidelines and local regulations * State that they are available for the trial duration Exclusion Criteria: * Presence of a major neurological or psychiatric disorder (including generalised anxiety, major depressive disorder, or an addiction to alcohol or drugs) according to ICD-10 and/or DSM 5 criteria * Under legal guardianship or incapacitation * History of cerebral disease (vascular, degenerative, physical malformation, tumor, or head trauma with loss of consciousness for more than an hour) which interferes with the aims of the study protocol * Presence of a chronic disease or acute unstable illness (respiratory, cardiovascular, digestive, renal, metabolic, hematologic, endocrine or infectious) which interferes with the aims of the study protocol * Current or recent medication that may interfere with cognitive action (psychotropic, systemic corticosteroid, anti-Parkinson's, or analgesic drugs). The interfering nature of the different treatments will be at the discretion of the investigating doctor. * Have regularly or intensively practiced meditation or comparable practices (yoga, Qi Gong, Alexander technique) * more than one day per week for more than six months consecutively over the last 10 years, * intensively (internship or retreat \> five consecutive days) over the past 10 years, * more than 25 days of retreats (cumulatively) prior to the last 10 years.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Clinical Research Memory Centre of Lyon (CMRR), department of the University Hospitals of Lyon - Hospices Civils de Lyon (HCL)
Lyon, France
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The Consorci Institut D'Investigacions Biomediques August Pi i Sunyer (IDIBAPS)
Barcelona, Spain
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The Department of Psychiatry at University of Cologne (UKK)
Cologne, Germany
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The Division of Psychiatry at University College London (UCL).
London, England, United Kingdom
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