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Can a 12-Week online program lift the mental health burden of psoriatic disease?

NCT ID NCT05571696

Symptom relief Sponsor: Elaine Husni Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a 12-week online program called Immune Strength for people with psoriasis or psoriatic arthritis. The program provided tips on stress, sleep, nutrition, and exercise, plus one-on-one email coaching from a wellness professional. Researchers wanted to see if this low-cost approach could reduce depression symptoms and improve overall well-being. The study included 84 adults from the Cleveland Clinic who had mild to moderate depression.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Immune Strength online coaching program
What this could lead to
If it works, this could offer a low-cost, scalable way to improve mental health for people with psoriatic diseases.
What could go wrong
This was a small, completed study with no control group, so results may not be widely applicable. The program requires computer and internet access, which may limit who can benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

84 people

The number who actually took part.

Started

Oct 2022

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patient of Cleveland Clinic * Adults (=18 years of age) * Diagnosis of psoriasis or psoriatic arthritis by a board certified physician. * PHQ9 score between 5 and 20 * Computer and internet access * A valid email address * Able to speak \& read English * Able to understand \& sign informed consent Exclusion Criteria: * PHQ9 score \> 20 * History of major depressive disorder * Currently receiving psychotherapy for major depressive disorder (MDD), anxiety or psychotic disorder * On a wait-list for psychotherapeutic treatment * Received treatment for a severe psychiatric illness in the previous 6 months * Demonstrate a notable suicidal risk at study visit

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Conditions

The condition(s) this trial relates to.

psoriasis psoriatic arthritis Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arthritis, psoriatic Psoriasis

Contacts and locations

Locations

  • The Cleveland Clinic

    Cleveland, Ohio, 44195, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.