Can a sugar-processing drug fix cystic fibrosis?
NCT ID NCT02325362
First seen Nov 20, 2025 · Last updated May 23, 2026 · Updated 28 times
Summary
This study tested whether miglustat, a drug used for other conditions, can help restore salt and water balance in the lungs of adults with cystic fibrosis. Sixteen adults with a specific genetic mutation (F508del) received miglustat or a placebo in a crossover design. The main goal was to measure changes in nasal chloride transport, a marker of CFTR protein function. The study was completed but results are not yet widely reported.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Assistance publique-Hôpitaux de Paris, Hôpital Cochin
Paris, 75014, France
Conditions
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