Could a common immune treatment help rare muscle-weakening disease?
NCT ID NCT06599697
First seen Nov 01, 2025 · Last updated May 20, 2026 · Updated 29 times
Summary
This study tests whether intravenous immunoglobulin (IVIG) can help people with a rare autoimmune muscle disease called anti-HMGCR IMNM. The disease causes muscle weakness and damage. The trial will include 12 adults with active disease who will receive either IVIG or a placebo every 4 weeks for 3 doses. The main goal is to see if IVIG lowers a muscle enzyme in the blood, which indicates less muscle damage.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ANTI-3-HYDROXY-3-METHYLGLUTARYL-COA REDUCTASE (HMGCR) IMMUNE-MEDIATED NECROTIZING MYOPATHY are added.
Genom att skicka in godkänner du våra Användarvillkor
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
Genom att skicka in godkänner du våra Användarvillkor
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Johns Hopkins University
NOT_YET_RECRUITINGBaltimore, Maryland, 21218, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
-
University of Pittsburgh
NOT_YET_RECRUITINGPittsburgh, Pennsylvania, 15260, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
-
University of Texas Health Science Center at Houston
ACTIVE_NOT_RECRUITINGHouston, Texas, 77030, United States
-
University of Washington
ACTIVE_NOT_RECRUITINGSeattle, Washington, 98195, United States
Conditions
Explore the condition pages connected to this study.