New heat therapy could free women from fibroid surgery
NCT ID NCT07235787
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a minimally invasive treatment called microwave ablation for uterine fibroids. It uses heat to shrink fibroids and reduce symptoms like heavy bleeding and pelvic pressure, while preserving the uterus. The study will enroll 20 premenopausal women with fewer than five fibroids, each smaller than 10 cm. Researchers will measure changes in fibroid size, bleeding, and hemoglobin levels at 3 and 6 months after the procedure.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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25 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Female patients aged 25 years or older Good general health Symptomatic uterine fibroids suitable for microwave ablation as determined by examining gynecologist Premenopausal status Acceptable risks for general anesthesia or sedation Number of fibroids: fewer than 5 Size of fibroid: less than 10 cm Exclusion Criteria: Ongoing anticoagulant treatment and/or known bleeding disorder Chronic diseases contraindicating general anesthesia Pregnancy Postmenopausal status 5 or more fibroids Fibroid size 10 cm or larger Poor general health precluding anesthesia or sedation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Assiut University
Asyut, Assiut Governorate, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Green tea and vitamin D3 may stop fibroids returning after surgery
- New surgical bag aims to keep fibroids contained during keyhole surgery
- Acupuncture meets medicine: new combo targets Post-Surgery nausea
- New study aims to find safest method to cut blood loss in fibroid surgery