New study aims to find safest method to cut blood loss in fibroid surgery
NCT ID NCT07352761
First seen Jun 25, 2026 · Last updated Jul 15, 2026 · Updated 3 times
Summary
This study compares four surgical techniques to temporarily block blood flow to the uterus during laparoscopic fibroid removal. The goal is to see which method best reduces blood loss and protects ovarian function. Sixty women with uterine fibroids will be randomly assigned to one of the four approaches.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify the best surgical technique to reduce blood loss during fibroid removal, improving safety and recovery.
- What could go wrong
- This is a small, early-stage trial (60 participants) comparing surgical procedures, not testing a new drug. Results may not apply to all patients or settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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May 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * women with uterine fibroids and complaining of either abnormal uterine bleeding, infertility, urinary or rectosigmoid pressure manifestations. * Fibroid size from 3 - 10 cm in diameter and with * a maximum number of 3 fibroids. Exclusion Criteria: * contraindication to pneumoperitoneum and laparoscopy, * patients with BMI \> 30 kg/m2, * history of midline abdominal incisions, * women with history of prior ovarian surgery, * women with history of hormonal treatment for the last 3 months before surgery, * women who are not good candidate for myomectomy and who would benefit more from hysterectomy such as, women with multiple ≥ 4 leiomyomata, associated adenomyosis, recurrent fibroids after myomectomy. * suspected endometrial malignancy or suspected leiomyosarcoma features on ultrasound and/or MRI. * Submucous fibroids who will undergo hysteroscopic myomectomy beside the laparoscopic surgery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Obstetrics and Gynecology, Faculty of Medicine, Alexandria Univeristy
Alexandria, El-Shatby, 21723, Egypt
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• Al-Madina Women Hospital, A specialized hospital of Obstetrics and Gynecology, Alexandria, Egypt.
Alexandria, Smouha, Egypt
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