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Radiation's hidden toll: study checks blood vessels of hospital workers

NCT ID NCT07363187

Knowledge-focused Sponsor: Istanbul Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to see if long-term, low-dose radiation exposure at work can cause early damage to small blood vessels in healthcare workers. Researchers will use a simple microscope test on the fingernail area and blood tests to look for signs of vessel and inflammation changes. The study will compare 90 exposed workers with non-exposed coworkers to better understand these early effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Feb 2026

An estimate. Start dates often move.

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will consist of healthcare workers aged 18 to 60 years employed at a tertiary care hospital. The exposed group will include healthcare workers with chronic occupational exposure to low-dose ionizing radiation, while the control group will include healthcare workers without occupational radiation exposure, working in non-radiation-related departments within the same institution. Participants will be recruited on a voluntary basis and will undergo a single study visit including nailfold capillaroscopy, blood sample collection, and completion of demographic and occupational exposure questionnaires.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthcare workers aged between 18 and 60 years. * For the control group: Employment in a healthcare institution with either occupational exposure to low-dose ionizing radiation or no occupational radiation exposure. * For the exposed group: chronic occupational exposure to ionizing radiation for at least 3 years. * Willingness and ability to provide written informed consent. * Ability to comply with study procedures, including nailfold capillaroscopy and blood sample collection. Exclusion Criteria: * History of cardiovascular disease, cerebrovascular disease, or peripheral vascular disease. * Presence of systemic diseases that may affect microvascular structure or endothelial function, including diabetes mellitus, uncontrolled hypertension, dyslipidemia, or chronic kidney disease. * Known autoimmune, connective tissue, or systemic inflammatory diseases (e.g., systemic sclerosis, lupus erythematosus, vasculitis). * Active infection or acute inflammatory condition at the time of enrollment. * Use of systemic medications that may affect endothelial function or microcirculation within the past 4 weeks, including vasodilators, antihypertensive agents, statins, antiplatelet or anticoagulant drugs. * Current smoking or history of smoking within the past 6 months. * Pregnancy or breastfeeding. * History of malignancy or current cancer treatment. * Previous finger trauma, surgery, or local conditions affecting the nailfold area that may interfere with capillaroscopic evaluation.

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Conditions

The condition(s) this trial relates to.

coronary microvascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endothelial dysfunction Microvascular dysfunction Occupational radiation exposure

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Istanbul Training and Research Hospital

    Istanbul, 34000, Turkey (Türkiye)

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