Tiny bug may warn of big infection in kids with cystic fibrosis
NCT ID NCT03947957
First seen Feb 28, 2026 · Last updated Jun 22, 2026 · Updated 21 times
Summary
This study follows 70 infants with cystic fibrosis to see if a specific germ (Porphyromonas catoniae) found in their body at 12 months old can predict whether they will get a serious lung infection with Pseudomonas aeruginosa by age 3. Researchers collect sputum, stool, and blood samples over time. The goal is to find a warning sign that could help doctors act sooner.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHRU Angers
Angers, France
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CHRU Nantes
Nantes, France
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CHRU Rennes
Rennes, France
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CHRU de Tours
Tours, France
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CHU Grenoble
Grenoble, France
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Centre de Perharidy
Roscoff, France
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Hôpital Charles Nicolle
Rouen, France
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Hôpital Femme-Mère-Enfant Lyon
Lyon, France
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Hôpital Necker
Paris, France
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Hôpital Trousseau
Paris, France
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Hôpital des Enfants Bordeaux
Bordeaux, France
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could help identify children with cystic fibrosis at highest risk for Pseudomonas infection, allowing earlier monitoring or intervention.
What could go wrong
This is an observational study, not a treatment trial. It only looks for a link between a biomarker and later infection; it does not test any therapy. The results may not lead to direct clinical changes.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.