Can a smile reveal hidden consciousness? new study investigates
NCT ID NCT06088628
First seen Jan 20, 2026 · Last updated Jun 22, 2026 · Updated 19 times
Summary
This study looks at micro-expressions—tiny, involuntary facial movements—in 200 patients with prolonged disorders of consciousness. Researchers will use emotional stimuli to trigger these expressions and combine them with EEG and MRI scans. The goal is to better classify levels of consciousness and explore remaining brain function.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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First Affiliated Hospital,Zhejiang University
RECRUITINGHangzhou, Zhejiang, 310003, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could improve how doctors diagnose levels of consciousness in patients with severe brain injuries.
What could go wrong
This is an early observational study, so it may not lead to immediate clinical changes. Results may not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.