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4,000 healthy adults scanned to stop heart disease before it starts

NCT ID NCT02508454

Knowledge-focused Sponsor: Baptist Health South Florida Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows 4,000 healthy adults aged 40 to 65 in the Miami area to find early, hidden signs of heart disease. Participants undergo advanced heart scans and blood tests at the start, then report their health yearly for years. The goal is to discover new ways to predict and prevent heart attacks and strokes before they happen.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors identify heart disease earlier and personalize prevention strategies.
What could go wrong
This is an observational study, not a treatment trial. It may not lead to direct changes in care, and results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 4,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2015

Expected to finish

Sep 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Since the MiHEART Study is primarily concerned with the determinants and natural history of subclinical cardiovascular disease, participants with known clinical disease will not be recruited. Most exclusion criteria relate to the long-term nature of the study or to incompatibility with certain study procedures. Eligibility (or ineligibility) status will be determined from self-reported information.

Ages

40 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Current full time/part-time employees of BHSF (occupational cohort) or resident of Greater Miami Area for at least six months (community cohort) * Age 40 to 65 years * Asymptomatic individuals free of any known cardiovascular event * Able to comprehend and sign an informed consent form Exclusion Criteria: * Prior history of major cardiovascular events (angina, myocardial infarction, prior coronary revascularization) * History of cerebrovascular disease including stroke and transient ischemic attack (TIA) * History of peripheral arterial disease (PAD) * History of either diagnosis or surgery for Abdominal Aortic Aneurysm (AAA) * Heart failure * Weight greater than 350 lbs * Any contraindication to CT scans or iodinated contrast * Active treatment for cancer * Currently pregnant, breastfeeding, or suspect they may be pregnant. * Patients who do not agree to an informed consent

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular disease

Contacts and locations

Locations

  • Raul Herrera

    Miami, Florida, 33176, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.