New hope for muscle stiffness: once-daily pill tested in myotonic dystrophy

NCT ID NCT06523400

Recruiting now Symptom relief Sponsor: Lupin Ltd. Source: ClinicalTrials.gov ↗

First seen Jan 27, 2026 · Last updated May 24, 2026 · Updated 17 times

Summary

This study tests whether a once-daily pill called mexiletine can safely reduce muscle stiffness (myotonia) in people with myotonic dystrophy types 1 and 2. About 176 adults aged 16 and older will take the drug or a placebo for 26 weeks. The main goal is to see if handgrip relaxation time improves.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aarhus University Hospital
RECRUITING

Aarhus, Denmark
Azienda Ospedaliera Universitaria Policlinico Tor Vergata
RECRUITING

Rome, Italy
Laboratory for Muscle Diseases and Neuropathies
RECRUITING

Leuven, Belgium
Ludug-Maximilians University
RECRUITING

München, Germany
Saint George's University Hospitals NHS Foundation Trust
RECRUITING

London, United Kingdom

Contact Email: •••••@•••••
University College Hospital
RECRUITING

London, United Kingdom
University Hospital of Madrid
RECRUITING

Madrid, Spain

Conditions

Explore the condition pages connected to this study.

MYOTONIC DYSTROPHY