New hope for muscle stiffness: once-daily pill tested in myotonic dystrophy

NCT ID NCT06523400

Recruiting now Symptom relief Sponsor: Lupin Ltd. Source: ClinicalTrials.gov ↗

First seen Jan 27, 2026 · Last updated May 05, 2026 · Updated 16 times

Summary

This study tests whether a once-daily medication called mexiletine can safely reduce muscle stiffness (myotonia) in people with myotonic dystrophy types 1 and 2. About 176 adults aged 16 and older will receive either the drug or a placebo for 26 weeks. The main goal is to see if handgrip relaxation time improves.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

Aarhus University Hospital
RECRUITING

Aarhus, Denmark
Azienda Ospedaliera Universitaria Policlinico Tor Vergata
RECRUITING

Rome, Italy
Laboratory for Muscle Diseases and Neuropathies
RECRUITING

Leuven, Belgium
Ludug-Maximilians University
RECRUITING

München, Germany
Saint George's University Hospitals NHS Foundation Trust
RECRUITING

London, United Kingdom

Contact Email: •••••@•••••
University College Hospital
RECRUITING

London, United Kingdom
University Hospital of Madrid
RECRUITING

Madrid, Spain

Conditions

Explore the condition pages connected to this study.

MYOTONIC DYSTROPHY