Lupin Ltd.

This study is testing whether a daily medication called mexiletine can safely reduce muscle stiffness and improve movement in people with myotonic dystrophy types 1 and 2. About 176 participants will take either the real drug or a placebo pill for 26 weeks to see if it helps them…

This study is testing whether a new once-daily version of the drug mexiletine works as well and is as safe as the standard three-times-daily version for people with rare muscle stiffness disorders called non-dystrophic myotonias. Twenty-four participants will try both versions fo…

This study is a long-term patient registry that will observe and collect information from children under 6 years old who have a myotonic disorder and are already being treated with the drug mexiletine. The main goal is to understand the long-term safety of this medication in very…