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Psoriasis drug showdown: methotrexate vs tofacitinib

NCT ID NCT07261306

First seen Jan 05, 2026 · Last updated May 23, 2026 · Updated 23 times

Summary

This study compares two oral medications, methotrexate and tofacitinib, to see which works better for chronic plaque psoriasis. It involves 75 adults aged 18-70 with moderate to severe psoriasis that hasn't responded well to topical treatments. The main goal is to measure how many patients achieve at least a 75% reduction in psoriasis severity after 12 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Lahore general hospital

    RECRUITING

    Lahore, Punjab Province, Pakistan

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.