Psoriasis drug showdown: which pill works best?

This study compares two oral medications, methotrexate and tofacitinib, to see which is more effective at reducing psoriasis plaques. It involves 75 adults with moderate to severe chronic plaque psoriasis who have not responded well to topical treatments. The main goal is to measure how many participants achieve at least a 75% improvement in their psoriasis severity after 12 weeks of treatment.