New combo therapy targets hard-to-treat arthritis patients
NCT ID NCT06301373
First seen Nov 01, 2025 · Last updated May 17, 2026 · Updated 27 times
Summary
This study looks at people with active rheumatoid arthritis who have a specific pattern in their joint tissue (called myeloid-stromal) that often leads to worse outcomes. Researchers want to see if starting treatment with two drugs—methotrexate and tofacitinib—works better than methotrexate alone. About 130 adults will take part, and the main goal is to see if more people get at least 20% improvement in symptoms after 12 weeks.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Foshan Hopsital of Traditional Chinese Medicine
RECRUITINGFoshan, Guangdong, 528000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pu Ning Shi Ren Ming Yi Yuan
RECRUITINGJieyang, Guangdong, 515300, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shenshan Medical Central, Memorial Hospital of Sun Yat-sen University
RECRUITINGShantou, Guangdong, 516621, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sun Yat-sen Memorial Hospital
RECRUITINGGuangzhou, Guangdong, 510120, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Affiliated Panyu Central Hospital of Guangzhou Medical University
RECRUITINGGuangzhou, Guangdong, 511400, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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