New combo therapy targets hard-to-treat rheumatoid arthritis patients
NCT ID NCT06301373
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 26 times
Summary
This study compares two treatments for adults with active rheumatoid arthritis who have a specific joint tissue type (myeloid-stromal) that often leads to poor outcomes. Participants will either receive standard methotrexate alone or methotrexate combined with tofacitinib for 12 weeks, with follow-up up to 48 weeks. The goal is to see if the combo improves symptoms and slows joint damage better than methotrexate alone.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Foshan Hopsital of Traditional Chinese Medicine
RECRUITINGFoshan, Guangdong, 528000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Pu Ning Shi Ren Ming Yi Yuan
RECRUITINGJieyang, Guangdong, 515300, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Shenshan Medical Central, Memorial Hospital of Sun Yat-sen University
RECRUITINGShantou, Guangdong, 516621, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sun Yat-sen Memorial Hospital
RECRUITINGGuangzhou, Guangdong, 510120, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Affiliated Panyu Central Hospital of Guangzhou Medical University
RECRUITINGGuangzhou, Guangdong, 511400, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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