Study finds no lung damage from common arthritis drug
NCT ID NCT07360340
First seen Jan 25, 2026 · Last updated Jun 22, 2026 · Updated 23 times
Summary
This study looked at 50 Egyptian patients with rheumatoid arthritis to see if methotrexate, a common treatment, causes lung problems. Half the patients took methotrexate, and the other half took other arthritis drugs. Researchers used lung function tests and CT scans to check for damage. They found no difference in lung health between the two groups, suggesting methotrexate may not be a major cause of lung disease in these patients.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Faculty of medicine, Ain Shams University
Cairo, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Methotrexate
What this could lead to
If confirmed, this could reassure patients that methotrexate may not cause lung damage in rheumatoid arthritis.
What could go wrong
This was a small, single-center study with only 50 patients. Results may not apply to all populations or detect rare side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.