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PCOS treatment showdown: metformin vs. birth control for older women

NCT ID NCT03905941

First seen Mar 02, 2026 · Last updated Jun 23, 2026 · Updated 17 times

Summary

This study aimed to see if metformin or birth control pills were more satisfying for treating PCOS in women aged 40-49. It planned to use a quality-of-life questionnaire to measure patient satisfaction. However, the study was withdrawn before any participants were enrolled, so no data was collected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Virginia

    Charlottesville, Virginia, 22901, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Metformin and oral combined hormonal contraceptives (ethinyl estradiol/norethindrone acetate)

What this could lead to

If it had succeeded, this could have helped guide treatment choices for PCOS in older women based on patient satisfaction.

What could go wrong

The study was withdrawn before enrolling any participants, so no results are available. It was also very early-phase and small in scope.

Conditions

The condition(s) this trial relates to.

polycystic ovary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.