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Can new ICU training save lives after breathing tube removal?

NCT ID NCT05523479

Knowledge-focused Sponsor: University of Pittsburgh Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at different training methods for ICU staff to improve how they remove breathing tubes from patients. It involves over 13,000 adults on ventilators for more than 24 hours. The goal is to see if better education and care plans can reduce deaths and increase use of helpful breathing support after tube removal.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 13,018 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2023

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * All adults treated with invasive mechanical ventilation \>24 hours in participating ICUs Exclusion Criteria: * None

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Conditions

The condition(s) this trial relates to.

acute respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute respiratory failure Airway extubation

Contacts and locations

Locations

  • UPMC Carlisle

    Carlisle, Pennsylvania, 17015, United States

  • UPMC Community Osteopathic

    Harrisburg, Pennsylvania, 17109, United States

  • UPMC East

    Monroeville, Pennsylvania, 15146, United States

  • UPMC Hanover

    Hanover, Pennsylvania, 17331, United States

  • UPMC Harrisburg

    Harrisburg, Pennsylvania, 17101, United States

  • UPMC Jameson

    New Castle, Pennsylvania, 16105, United States

  • UPMC Magee-Womens Hospital

    Pittsburgh, Pennsylvania, 15213, United States

  • UPMC Memorial

    York, Pennsylvania, 17408, United States

  • UPMC Mercy

    Pittsburgh, Pennsylvania, 15219, United States

  • UPMC Northwest

    Seneca, Pennsylvania, 16346, United States

  • UPMC Passavant

    Pittsburgh, Pennsylvania, 15237, United States

  • UPMC Presbyterian

    Pittsburgh, Pennsylvania, 15213, United States

  • UPMC Shadyside

    Pittsburgh, Pennsylvania, 15232, United States

  • UPMC St. Margaret

    Pittsburgh, Pennsylvania, 15215, United States

  • UPMC West Shore

    Mechanicsburg, Pennsylvania, 17050, United States

  • UPMC Williamsport

    Williamsport, Pennsylvania, 17701, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15213, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.