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New brain bleed treatment shows promise in massive review

NCT ID NCT06181994

Disease control Sponsor: Montefiore Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks back at medical records of 5,000 adults who had a procedure called middle meningeal artery embolization (MMAE) for chronic subdural hematoma, a condition where blood collects on the brain. The goal is to see how well the procedure works, how often the blood comes back, and how safe it is. Researchers want to learn if this less invasive treatment can help patients avoid repeat surgeries.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 5,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2023

Expected to finish

Aug 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with chronic subdural hematoma

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Consecutive adult patients (18 yrs. of age or older) * Endovascular embolization of middle meningeal artery using any embolization material: PVA particles; Onyx, nBCA glue; dimethyl sulfoxide, microcoils, PVA with microcoils Exclusion Criteria: * Endovascular embolization of middle meningeal artery using any other embolization material

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Conditions

The condition(s) this trial relates to.

Hematoma, Subdural, Chronic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic subdural hematoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    10 sites in 3 countries. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Austin Health

    RECRUITING

    Heidelberg, Victoria, 3084, Australia

  • Baptist Health South Florida, Inc.

    RECRUITING

    Coral Gables, Florida, 33143, United States

  • Beth Israel Deaconess Medical Center (BIDMC)/Harvard Medical School

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Geisinger Health

    COMPLETED

    Danville, Pennsylvania, 17822, United States

  • HCA Houston Healthcare Kingwood

    COMPLETED

    Kingwood, Texas, 77339, United States

  • Lahey Hospital and Medical Center

    RECRUITING

    Burlington, Massachusetts, 01805, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic

    COMPLETED

    Rochester, Minnesota, 55905, United States

  • Mayo Clinic Florida

    COMPLETED

    Jacksonville, Florida, 32224, United States

  • Montefiore Medical Center

    RECRUITING

    The Bronx, New York, 10467, United States

  • Orlando Regional Medical Center

    RECRUITING

    Orlando, Florida, 32806, United States

  • The University of Iowa

    COMPLETED

    Iowa City, Iowa, 52242, United States

  • Thomas Jefferson University

    RECRUITING

    Philadelphia, Pennsylvania, 19144, United States

  • Toronto Western Hospital

    COMPLETED

    Toronto, Ontario, M5T 2S8, Canada

  • UTHealth Houston

    COMPLETED

    Houston, Texas, 77030, United States

  • Unity Health Toronto

    COMPLETED

    Toronto, Ontario, M5C 2T2, Canada

  • University of Chicago Medicine

    RECRUITING

    Chicago, Illinois, 60637, United States

  • University of Illinois Chicago

    COMPLETED

    Chicago, Illinois, 60607, United States

  • University of Toronto

    RECRUITING

    Toronto, Ontario, M5S 1A1, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.