Can a sticky film shield breast cancer patients from radiation burns in tropical heat?
NCT ID NCT07729423
First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time
Summary
This trial tests whether a silicone film called Mepitel Film can prevent radiation dermatitis — painful skin irritation — in breast cancer patients undergoing radiation therapy in Singapore's hot and humid weather. About 60 adults who have had breast cancer surgery and are scheduled for radiation will wear the film on their skin during treatment. Researchers will track how often the film needs replacement and compare skin reactions to data from a similar study in Canada.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- a silicone film called Mepitel Film applied to the skin during radiation therapy
- What this could lead to
- If it works, this could offer a simple way to prevent painful skin burns during radiation therapy, even in hot and humid climates.
- What could go wrong
- This is a small feasibility study, not a large trial. The film may not stick well in heat and humidity, or it may not reduce skin reactions as hoped.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2025
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
National University Hospital
- Ages
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21 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 21 years old (legal age of maturity in Singapore) * Male or female * Informed consent * Patients have undergone a mastectomy with or without reconstruction or breast-conserving surgery. * Histological confirmation of breast carcinoma (invasive or in situ carcinoma) * Patients are scheduled to receive hypofractionated (40Gy in 15 daily fractions or 26Gy in 5 daily fractions) photon-based RT * Patient treated with or without tissue the addition of equivalent bolus and/or boost. * Can communicate in English or be aided by a translator. Exclusion Criteria: * Prior RT to any portion of the planned treatment site. * Patients will receive partial breast external beam RT, proton beam therapy, or brachytherapy. * Patients with active rash, pre-existing dermatitis, or other conditions within the treatment area may make skin assessment for the study difficult per treating physician discretion. * Known history of adhesive, tape or silicon allergy or sensitivity. * Concomitant cytotoxic chemotherapy * Bilateral breast pathology requiring concurrent bilateral breast or chest wall RT. * Current inflammatory breast cancer or gross dermal involvement at initiation of RT. * Patient has a Karnofsky Performance Status score \<60.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National University Hospital
RECRUITINGSingapore, Singapore
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a common steroid shield breast cancer patients from a dangerous drug side effect?