Mind over movement: mental rehearsal may smooth arm function after stroke
NCT ID NCT07507552
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a single session of a mental practice technique called PETTLEP-based Action Observation and Motor Imagery (AOMI) can immediately improve arm movement in stroke survivors. Participants will either watch and mentally rehearse a reach-to-grasp task or do a control relaxation activity. Researchers will use a smartphone-based motion capture system to measure smoothness and compensatory body movements.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- PETTLEP-based Action Observation and Motor Imagery (AOMI) - a mental practice technique
- What this could lead to
- If it works, this could point toward a simple, drug-free way to help stroke survivors move their arm more smoothly and rely less on their body to compensate.
- What could go wrong
- This is a very small, early study (28 people) testing only immediate effects after a single session. It may not lead to lasting improvements or work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 28 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Apr 2026
An estimate. Start dates often move.
- Expected to finish
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Mar 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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40 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female and male adults aged 40 to 80 years with a diagnosis of unilateral ischemic or hemorrhagic stroke. * Residual voluntary movement activity of the affected upper limb. * Mild to moderate spasticity (Modified Ashworth Scale ≤ 3). * Adequate cognitive function to understand and follow verbal instructions (Mini-Mental State Examination ≥ 21). * Medically stable patients, with no active or uncontrolled systemic illness. * Ability to sit unsupported for at least 30 minutes and be able to perform brief cognitive-motor exercises. Exclusion Criteria: * Other central nervous system disorders (e.g., Parkinson's disease, multiple sclerosis, traumatic brain injury). * Musculoskeletal or orthopedic conditions causing restriction of movement in the upper-limb (such as fixed contractures, severe joint deformities, shoulder subluxation). * Severe sensory deprivation, visual neglect, or inattention that interferes with completion of the task or the ability to engage in motor imagery. * Uncontrolled seizures, severe cardiovascular instability, or any other contraindication to imagery.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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