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Sleep loss hits women differently depending on their cycle

NCT ID NCT05381532

Knowledge-focused Sponsor: Brigham and Women's Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study looked at how healthy women in their 20s and 30s respond to sleep loss at different points in their menstrual cycle. Researchers measured alertness, sleepiness, hormone levels, and body temperature in a controlled lab setting. The goal is to understand if menstrual phase changes how sleep deprivation affects the body.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help tailor sleep recommendations to a woman's menstrual cycle, improving alertness and well-being.
What could go wrong
This is a small, early-stage observational study with only 29 participants. Results may not apply to all women or real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

29 people

The number who actually took part.

Started

Oct 2022

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 35 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female * 18-35 years old * Regular menstrual cycle between 26-35 days in duration * Not using any form of hormonal contraception for at least the prior 3 months * Regular sleep patterns (7-9 hours/night) * Not taking any medications or supplements * Weight \>110 lb * BMI between 18.5 and 29.5 kg/m2 Exclusion Criteria: * Primary sleep disorder * History of shift work * Transmeridian travel in the previous 3 months * Presence of acute or chronic disease, including but not limited to: diabetes, metabolic disorders, psychiatric illness, reproductive disorders * Current pregnancy, \< 6 months postpartum, and/or breastfeeding * Blood donation in the past 8 weeks * Extreme morning or evening chronotype

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Conditions

The condition(s) this trial relates to.

Sleep Deprivation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Sleep deprivation

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.