Two brain sensors could catch drowsiness before it turns deadly
NCT ID NCT05453643
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers are testing whether two EEG sensors can reliably measure sleepiness caused by sleep loss or disrupted sleep cycles. About 40 healthy adults with no sleep complaints take part in lab sessions that include extended wakefulness, interrupted sleep, simulated driving, and attention tasks every four hours. The goal is to build methods that predict drowsiness-related attention lapses and lower the risk of accidents tied to secondary hypersomnolence.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- sleep deprivation patterns and EEG-based drowsiness monitoring
- What this could lead to
- If it works, this could give drivers and workplaces a simple two-sensor way to spot dangerous drowsiness before it causes an accident.
- What could go wrong
- The study is small and tests drowsiness in a lab, not real driving, so the sensor readings may not translate to real-world crash prevention. EEG signals also vary between people, which can make automated detection unreliable.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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Mar 2023
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * BMI between 18 and 27, * With a score on the PHQ-4 scale less than or equal to 2 for scores A (Anxiety) and D (Depression), * Subjects with no complaints of excessive daytime sleepiness (total ESS score \<11), * Non-professional drivers, * Subjects who have held their driving license for at least one year, * Subjects affiliated to a social security scheme, * Subjects able to understand the study, * Subjects available to come to the 3 visits required by the study, * Free, informed and written consent signed Exclusion Criteria: * Pathologies that can induce excessive daytime sleepiness: untreated narcolepsy or idiopathic hypersomnia, untreated restless legs syndrome, untreated periodic leg movement syndrome, * Chronic insomnia disorder, * Excessive alcohol consumption (\> 2 glasses per day) during the last 6 months, * Excessive consumption of coffee, tea or cola-type caffeinated beverages (\> 5 cups/day), * Severe pathologies involving the vital prognosis in the short term, * Uncontrolled endocrine pathologies (dysthyroidism, diabetes), * All progressive cardiac pathologies, treated or untreated, * All progressive neurological conditions treated or not (brain tumor, epilepsy, migraine, stroke, sclerosis, myoclonus, chorea, neuropathy, muscular dystrophies, myotonic dystrophy, etc.), * Substance dependence, * Shift workers or night workers who have performed on-call or on-call duty in the last 72 hours, * Patients taking psychotropic drugs (antidepressants, antihistamines), * Long-term treatment with benzodiazepines and z-drugs, * Patients on cardiotropic, * Deprived of liberty by a judicial or administrative decision, * Pregnant or breastfeeding woman, * Subject under legal protection (guardianship, wardship) or deprived from his rights following administrative or judicial decision
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CHU bordeaux
Bordeaux, 33076, France
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Other studies related to the condition(s) this trial covers.
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