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Period blood may hold key to endometriosis diagnosis

NCT ID NCT05601596

Diagnosis Sponsor: Northwell Health Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a simple menstrual blood sample can help predict endometriosis in women aged 18-40 with symptoms like pelvic pain. Researchers will analyze cells in the blood to find patterns linked to the disease. The goal is to create a test that helps decide if surgery or hormone therapy is needed, avoiding unnecessary procedures.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2022

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The cohort will enroll a total of 250 menstruating individuals in total; 108 control subjects who self-report the general absence of symptoms of endometriosis and 142 symptomatic cases who report chronic symptoms\* of endometriosis but who have not yet been diagnosed and are seeking physician evaluation for their symptoms.

Ages

18 to 40 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For All * 18 to 40 year old menstruating women (continue to get cycles) * More than a light menstrual flow (light flow is soaking less than 1 thin pad or light tampon in 4 hours at peak flow) * Willingness to provide two menstrual samples across two separate menstrual cycles. * Willingness to provide a DNA sample (obtained via menstrual blood or cheek swab) For Controls: •General Absence of \*symptoms suggestive of endometriosis which includes: 1-Chronic pelvic pain 2-Painful menses 3-Pain during intercourse 4-Pain going to the bathroom 5-Abdominal bloating (BUT MUST NOT Include): 6-Report of missed days of work, school, athletic,social and/or other activities due to related pain and discomfort For Symptomatic: * Consistently Experiencing chronic symptoms of endometriosis\* * Without definitive diagnosis (i.e. pathology report following diagnostic surgery) * Seeking physician evaluation (considered by physician to be a candidate for laproscopic surgery * Willingness to provide at least one of the menstrual samples PRIOR to planned surgery * Surgical and pathological confirmation of endo (or NOT) Exclusion Criteria: For All: * under age 18 or over 40 years * Unable/unwilling to provide a menstrual sample * Light menstrual flow (light flow is soaking less than 1 thin pad or light tampon in 4 hours at peak flow) * Diagnosed with endometriosis CONTROL: * More than 1 symptom of endometriosis\* * Report of missed days of work, school, athletic, social and/or other activities due to related pain and discomfort Symptomatic: Unable to provide a menstrual sample prior to surgery

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Conditions

The condition(s) this trial relates to.

disease endometriosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endometriosis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Feinstein Institutes/Northwell health

    Manhasset, New York, 11030-3816, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.